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This book analyses the connotation and theoretical progress of international science, technology and innovation centres, combs through the policies and practices of science, technology and innovation development in the Guangdong, Hong Kong and Macao Greater Bay Area, compares the three modes of construction of the world's major international science, technology and innovation centres, and proposes the modes and main paths that should be adopted for the construction of an international science, technology and innovation centre in Guangdong, Hong Kong and Macao based on the developmental realities, strategic positioning and objectives of the Guangdong, Hong Kong and Macao Greater Bay Area.